Imagine you're counseling a couple who have undergone carrier screening for Tay-Sachs disease. The man is a carrier, and the woman does not carry the Tay-Sachs allele. How should you advise them?

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Explanation:

Tay–Sachs disease is a disorder in genetic trait that results in the damage of nerve cells in the spinal cord and the brain. The most regular type, identified as an infantile Tay–Sachs disease, becomes noticeable around 3 to 6 months of age with the baby losing the capability to sit, turn over, or crawl.

Since one of the couple in question is a carrier and not both, then they should be informed that if they have a child, the child will not have Tay-Sachs disease but will have a 50% chance of being a carrier of the Tay-Sachs allele.

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