Which of the following was a significant challenge in building the Panama Canal? A. Mosquitoes spread diseases to workers.

B. Engineering plans were often wrong.

C. Workers went on strike to get extra pay.

D. Congress did not provide enough money.

a. mosquitoes spread diseases to workers.

The one that is significant challange in building the Panama Canal is letter A or the frequent rains caused rivers to flood . The other challenge in building the Panama Canal is the outbreak of Malaria or the so-called yellow fever; it killed more then 20000 people

as general terms,  indian territory,  the indian territories, or  indian country  describe an evolving land area set aside by the  united states government  for the relocation of  native americans  who held  aboriginal title  to their land. in general, the tribes ceded land they occupied in exchange for  land grants  in 1803. the concept of an indian territory was an outcome of the 18th- and 19th-century policy of  indian removal. after the  civil war(1861–1865), the policy of the government was one of  assimilation.

the answer is b: an economic crisis throughout the country.