How did European trade routes in the Eastern Hemisphere change after the 16th century?

they had to stopped being central and start finding new route places around such as Africa.

Explanation:

I did a little bit of research

no statements but ok.

the statement that best describes the idea of manifest destiny that was used in the 19th century would be that "it was fate that the united states would continue to  expand westward," since people thought the us was "destined" to do so. 

the answer is a, salt plain