Leptin is an adipocyte hormone that send signals to the brain to "eat less" and "metabolize more." What is the explanation for why leptin injections cause weight loss in the strain of ob/ob mutant mice, but leptin injections has no effect in the majority of people?

Which popular american sandwich is made by placing a beef patty inside a bun?is an american classic prepared by placing a fried or barbequed beef patty in a bun.

What regulations are provided to ensure that the physical location of a childcare center conforms to required regulations set by the respective governing body of that area?

George’s daughter was born with a hole in her heart. he met up with a group of individuals of questionable character who agreed to deliver to george a healthy heart that could be a transplant for his daughter for a sum of $20,000. the group george negotiated with failed to deliver the heart. george tried to sue when he did not receive the heart but was surprised when the courts would not enforce the agreement.can george force performance of this contract? why or why not? (10 points)will he be able to recover the $20,000 that he gave for the heart? why or why not? (10 points)