The Na+-K+ ATPase uses the free energy of ATP hydrolysis in an active transport process to move Na+ and K+ across a membrane. What would the rate of nonmediated transport be given that the permeability coefficient for K+ through a human erythrocyte membrane is 2.4 × 10-10 cm/s. K+ ions must be moved from a concentration of 4 mM on the outside of the cell to 155 mM inside the cell?

The rate of non-mediated transport is mM/s.

Explanation:

Formula to calculate non-mediated transport is as follows.

           J =

where,  J = net rate of transportation

             P = permeability coefficient = cm/s

  = higher concentration region = 155 mM

  = low concentration region = 4 mM

Putting the given values into the above formula as follows.

          J =

         J =

            = mM/s

Therefore, we can conclude that the rate of non-mediated transport is mM/s.

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