If a mouse is given a dose of radiation sufficient to destroy its immune system, then injected with purified hematopoietic stem cells, what should happen?

A-

The mouse survives over 3 months and if successful transplantation

of their new HSCs rescues a second lethally irradiated recipient,

they can be considered to have received near pure HSC,

reconstituting their immune system.

B-

The mouse's remaining immune cells will cause a graft versus host

immune reaction, targeting the new HSCs for destruction.

C-

The new HSCs will over proliferate and the mouse will develop

leukemia.

D- the mouse dies as its immune system might attack the HSC.​