Allergic reactions are a result of the production and release of histamines from mast-cell granules. which of the following best explains a way in which antihistamines may affect signal transduction in an individual taking these drugs? A. The inhibit cellular response by binding to mast cell granules and eliminating the production of histamine.

B. They prevent pathway initiation by preventing the signaling molecule from binding to its receptor.

C. They produce a second messenger that interrupts in reverse is the direction of the signaling pathway.

D. They reduce the amount of histamine in the bloodstream by binding to and inactivating histamine.