Biology, 11.06.2020 03:57 pineapplepizaaaaa
The Smac protein in this paper is normally released from mitochondria during apoptosis, and its function is to accelerate apoptosis by binding to and inhibiting other proteins that inhibit apoptosis (it is thus somewhat like a second messenger in a signaling pathway).A. Smac contains four contiguous amino acids, Ala-Val-Pro-Ile, that bind to its target proteins. Its Kd for binding is about 100 nM. The compound at right was found to bind to the same site on the same target protein with a Kd of 12 nM. Based on these data, and the compound’s structure, which of the four amino acids do you think is least important in binding to target proteins? Explain. B. The four amino acids listed above are at the N-terminus of Smac, and the 11 missing GFP amino acids are at the C-terminus. How do you suppose the binding of Smac to its targets is affected (if at all) when Smac binds to the remainder of GFP? Explain
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15 ! come and answer! a(n) is the general term for an infectious disease that has spread across a city, region, or country.
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Compare the composition of the moon's surface with the composition of the earth's surface.
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The Smac protein in this paper is normally released from mitochondria during apoptosis, and its func...
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