What interaction between american indians and european colonists was most important? why?

Thanksgiving because we all got along
Hope it helped

Thanksgiving which took place in Plymouth in. 1621, when they all ate a meal and the Native Americans helped the Pilgrims survive

This question is an opinionated one, and we don’t know anything about the module or anything, thus we can not answer it. but if you are having trouble on what it is asking basically it is just asking to (using your knowledge on the topic) say which topics you were most interested and which were the most challenging.hope this : p