By 1850, of the 3.2 million slaves in the country's fifteen slave states, 1.8 million were producing cotton; by 1860, slave labor was producing over two billion pounds of cotton per year.

answer; ok in rural area most people depend on private transportation(cars),pick up truck,donkey and buggy: ),and urban people can walk or ride public transportation,bus,train cab,uber.

explanation:

allergens: overstimulate the nerve system

neurotics: attack nerve cells

mutagens: damage or otherwise alter dna sequence

generators: cause defects during growth and development  

carcinogens: cause unchecked cell growth

i hope you get the idea according to me these are the effects that happened.