According to Hans Selye, resistance to stress is lowest at the stage of the general adaptation syndrome.

they encountered severe weather for which they were poorly prepared.

answer; passive listening;

it might look like that the ideal way to research the health effects of trans fats is through a controlled experimental feeding trial. but these kinds of trial have several important limitations that the researcher must look into:

short in duration (this factor usually checks up on the intermediary risk factors rather than the actual outcomes of the disease)

limited dietary changes

only makes use of healthy participants