One difference between the Cherokee culture of the Southeast and Pueblo groups is that the Pueblo groups lived in the deserts of the Southwest. the Pueblo groups lived in the woodlands of the Northeast. the Pueblo groups lived on the coast of the Northwest. the Pueblo groups lived on the Great Plains.

One difference between the Cherokee culture of the Southeast and Pueblo groups is that:

the Pueblo groups lived in the deserts of the Southwest. (letter A)

Explanation:

Groups belonging to the Cherokee culture lived mainly in the Southeast of the United States. Puebloans, or Pueblo groups, on the other hand, inhabited mainly the deserts of the Southwest. Pueblo peoples share agricultural practices as well as religious ones, and are currently mostly found in the state of New Mexico. The name Pueblo comes from the Spanish word meaning "village," used by Spanish colonizers to refer to the residence style of these Native Americans.

the correct answer is a