What is the connotation of the phrase "joyless realms," as it is used here?
A) It suggests rage and anger.
B) It suggests struggle and trial.
C) It suggests joy and contentment.
D) It suggests misery and misfortune.

there are treatment options for depression (mdd) that may work for you. one way of treating depression may be to affect the levels of certain chemicals that brain cells use to communicate, called neurotransmitters. scientists believe that certain neurotransmitters may be out of balance in depression.

although the exact way depression medications shown to ease overall depression symptoms in some people work is unknown, scientists think that some medications work by affecting the levels of a neurotransmitter called serotonin in the brain. other treatments work by affecting the levels of other neurotransmitters like norepinephrine or dopamine.

question - in 1827, john walker, a druggist in a small english town, tipped a splint with sulphur, chlorate of potash, and sulphid of antimony, and rubbed it on sandpaper, and it burst into flame. the druggist had discovered the first friction-chemical match, the kind we use to-day. it is called friction-chemical because it is made by mixing certain chemicals together and rubbing them. although walker's match did not require the bottle of acid, nevertheless it was not a good one. it could be lighted only by hard rubbing, and it sputtered and threw fire in all directions. in a few years, however, phosphorus was substituted on the tip for antimony, and the change worked wonders. the match could now be lighted with very little rubbing, and it was no longer necessary to have sandpaper upon which to rub it. it would ignite when rubbed on any dry surface, and there was no longer any sputtering. this was the phosphorus match, the match with which we are so familiar. according the paragraph what was the benefit of the new phosphorus match? it burst into flame when rubbed on sandpaper. it was made by mixing chemicals. it could be ignited on any dry surface. it threw fire in all directions.

answer - matches required natural chemicals

answer; exploratory;