In a follow-up study examining the motivations that led to the overeating associated with obesity, many respondents pointed to a rewarding sense of pleasure they felt after eating large portions of high-calorie foods. this sense is mostly closely associated with activation of the:

mesolimbic pathway

Explanation:

Mesolimbic pathway  transports dopamine to the nucleus accumbens, amygdala, and hippocampus, which is suited in the brain. The nucleus accumbens is found in the ventral medial portion of the striatum and is believed to play a role in reward, desire, and the placebo effect. The amygdala and hippocampus are key components of the limbic system and are associated with emotion and memory formation, respectively. The cognitive sensations that are associated with this pathway, suggest that the mesolimbic pathway is involved in conditions such as addiction and depression 

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