What is most likely to occur when the brain is repeatedly flooded with artifical oopiates?

The Brain stops to produce Endorphins.

Explanation: Endorphins are special chemical substances produced by the Human body,it is produced in different organs especially areas of pain and stress and also in the Brain, Endorphins reacts with optiate receivers in order to help reduce the impact of pains and stress on the Human body,endorphins also helps to transmit electric signals through the nerves. When the Brain is repeatedly flooded with artificial opiates(drugs that tries to act like natural opiums) it causes the Brain to stop the production of Endorphins.

earlier philosophers whose work influenced the enlightenment included bacon, descartes, locke, and spinoza. the major figures of the enlightenment included beccaria, diderot, hume, kant, montesquieu, rousseau, adam smith, and voltaire. it spread the ideas of the enlightenment across europe and beyond.

for many centuries there were important factors which the economies of the muslim empires developed increasingly. they applied economic procedures in production, investment, finance, taxation and property. they used to tax certain goods (for example: harvest), they charged interest on money lent, they signed contracts with merchants; they relied on a common currency, and they used checks as well as promissory notes. with the money collected by means of taxation, the government provided the needy with an income. in addition, trading networks covered huge distances, so far regions started to have contact and exchange goods. this trade network covered areas of asia, africa and europe.