What are the effects on the brain if you use this opioid

Which one of the following research methods can show cause and effect

Polly is pushing a box across the floor with a force of 30 n. the force of gravity is –8 n, and the normal force is 8 n. which value could describe the force of friction if polly could not move the box?

Assume that a person skiing high in the mountains at an altitude of h = 15100 ft takes in the same volume of air with each breath as she does while walking at sea level. determine the ratio of the mass of oxygen inhaled for each breath at this high altitude compared to that at sea level. assume that the air composition (i.e. % of air that is oxygen) is the same at sea level as it is at 15100 ft.