In what situations do Newton’s laws of motion NOT apply?

In a naive or very general sense, it appears that Newton's combined first and second law, F = ma , does not always work. On a fairground ride such as a merry-go-round, or on a turning bus, unrestrained objects have unexplained horizontal accelerations.

answer; ///i do believe that the correct answer is ; ///(physical change);

not too sure thinking it will always be directed towards the centre of the earth. could be wrong not sure