In classical thermodynamics the (non-normalized) probability for a single particle amongst a large number of identical particles to have an energy e is given by p(e) = exp(− e kbt ). suppose the energy of the particles in question takes the form e = ax2 , where a is a positive constant, and x is a variable ranging (in whatever units are appropriate) from zero to infinity. show that the average energy for this system is given by hei = kbt 2 . this is known as the equipartition theorem.

Asubject in a clinical research trial experiences a serious, unanticipated adverse drug experience. how should the investigator proceed, with respect to the irb, after the discovery of the adverse event occurrence? a. do not report the adverse drug experience to the irb since it is a common adverse experience.b. report the adverse drug experience to the irb only if there are several other occurrences.c. report the adverse drug experience as part of the continuing review report.d. report the adverse drug experience in a timely manner, in keeping with the irb's policies and procedures, using the forms or the mechanism provided by the irb.