Name three anatomical/physiological or biochemical reasons why the liver is a frequent target organ of many chemical-induced toxicities. Explain how the selective induction of either Phase I (oxidative enzymes - e. g., cytochrome P-450) or Phase II (conjugative enzymes - e. g., glutathione transferase) enzymes can increase the toxicity of some chemicals while decreasing the toxicities of others.

The membrane surrounding a bone is the

Anurse is instructing a client who has a new prescription for a daily dose of lovastatin extended release. which of the following information should the nurse include in the teaching? a. report to the clinic for quarterly monitoring of kidney function while taking this medication. b. mix with applesauce after crushing if the medication is difficult to swallow. c. avoid consuming dairy products while taking this medication. d. take the medication with the evening meal.

Anurse on a medical unit is administering heparin by continuous iv infusion to a client who has a pulmonary embolism. the client’s most recent aptt is 70 seconds. which of the following actions should the nurse take? a. increase the iv infusion rate. b. decrease the iv infusion rate. c. discontinue the iv infusion. d. continue the iv infusion.