A 74 year old male suffered a burn to his lower leg 15 years ago which was treated with debridement and skin graft. Past medical history of non-insulin dependent diabetes for 30 years, hypertension, and coronary artery disease. His leg wound has always required some dressings and has never completely healed. It has recently changed and become more open and friable, and has increased drainage. What is the most the most appropriate next step in his management is

Ms. b is a 40-year-old woman who is the ceo of a struggling company. lately she has been experiencing headaches that are so severe that she gets dizzy and nauseated, and she is unable to carry out her usual daily routines. she reports that they usually begin as a throbbing pain in the left temple and then seem to spread throughout her head. a diagnosis of migraine headache is made after several tests. based on the patient history and signs and symptoms, discuss this type of headache and its physiological causes. discuss the available treatments to prevent and/or relieve the patient’s migraine.