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Experimental research, often considered to be the “gold standard” in research designs, is one of the most rigorous of all research designs. In this design, one or more independent variables are manipulated by the researcher (as treatments), subjects are randomly assigned to different treatment levels (random assignment), and the results of the treatments on outcomes (dependent variables) are observed. The unique strength of experimental research is its internal validity (causality) due to its ability to link cause and effect through treatment manipulation, while controlling for the spurious effect of extraneous variable.

Experimental research is best suited for explanatory research (rather than for descriptive or exploratory research), where the goal of the study is to examine cause-effect relationships. It also works well for research that involves a relatively limited and well-defined set of independent variables that can either be manipulated or controlled. Experimental research can be conducted in laboratory or field settings. Laboratory experiments , conducted in laboratory (artificial) settings, tend to be high in internal validity, but this comes at the cost of low external validity (generalizability), because the artificial (laboratory) setting in which the study is conducted may not reflect the real world. Field experiments , conducted in field settings such as in a real organization, and high in both internal and external validity. But such experiments are relatively rare, because of the difficulties associated with manipulating treatments and controlling for extraneous effects in a field setting.

Experimental research can be grouped into two broad categories: true experimental designs and quasi-experimental designs. Both designs require treatment manipulation, but while true experiments also require random assignment, quasi-experiments do not. Sometimes, we also refer to non-experimental research, which is not really a research design, but an all-inclusive term that includes all types of research that do not employ treatment manipulation or random assignment, such as survey research, observational research, and correlational studies.

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Chemotherapy works by stopping or slowing the growth of cancer cells, which grow and divide quickly. It can also harm healthy cells that divide quickly, such as those that line your mouth and intestines or cause your hair to grow. Damage to healthy cells may cause side effects. Chemotherapy kills cells that are in the process of splitting into 2 new cells. Because cancer cells divide much more often than most normal cells, chemotherapy is much more likely to kill them. Some drugs kill dividing cells by damaging the part of the cell's control centre that makes it divide.