A pharmacist is looking for a drug which will prevent an enzyme from working by binding to it as an inhibitor. Which of the inhibitors listed as choices will prove most effective, given equality in other considerations such as solubility, toxicity and stability? a. Substance Y, Kd = 23
b. Substance Z, Kd = 0.05
c. Substance X, Kd = 2.7
d. Substance P, Kd = 0.001

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Anurse is teaching a client about nitroglycerin sublingual tablets. which of the following statements by the client indicates an understanding of the teaching? a. “this medication has a slower onset than a nitroglycerin pill that is swallowed.” b. “i should take this medication as soon as pain begins.” c. “i can crush this medication for faster relief.” d. “this medication should completely dissolve within 15 minutes.”

Anurse is discussing adverse reactions to pain medications in older adult clients with a newly licensed nurse. which of the following findings should the nurse include as risk factors for an adverse drug reaction? (select all that apply.) a. decreased percentage of body fat b. polypharmacy c. multiple health problems d. increased rate of absorption e. decreased renal function