1. [20%] Blood coagulation and clot formation in humans is a complicated process with at least 13 different plasma coagulation factors involved. One of the more important protein factors is called
prothrombin, which must be converted into the enzyme thrombin for coagulation to occur. Individuals with
vitamin K deficiency are thought to have low prothrombin levels as a result.
Twenty patients with vitamin K deficiency were randomly chosen and their prothrombin levels were
measured. The mean prothrombin level for the sample was 20 (mg/100 ml) and the sample standard
deviation was 11 (mg/100 ml2). Calculate 95% confidence intervals for the population mean from these
statistics.
Solution:
a) What is a ?
b) What is critical value Za/2 orta/2?
M
8:2