How did the Patient Protection and Affordable Care Act fit the example of elastic clause Nesessary and proper clause?

Asubject in a clinical research trial experiences a serious, unanticipated adverse drug experience. how should the investigator proceed, with respect to the irb, after the discovery of the adverse event occurrence? a. do not report the adverse drug experience to the irb since it is a common adverse experience. b. report the adverse drug experience to the irb only if there are several other occurrences. c. report the adverse drug experience as part of the continuing review report. d. report the adverse drug experience in a timely manner, in keeping with the irb's policies and procedures, using the forms or the mechanism provided by the irb.

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What should you do when making a personal appeal to a procrastinator to change his/her work habits? a. use examples of how you were able to overcome procrastination to convince him/her to change. b. relay information you have heard from co-workers. c. do not give any personal information. d. explain how you have been personally impacted by his/her procrastination.