In carolina, conflict with indians occurred, but similar problems did not take place in pennsylvania because:

Fair land treaties were created--William Penn made it a priority to treat natives fairly for their land. 

The Pennsylvania colony was created by William Penn, a Quaker, who believed all people were equal. He created land treaties with the Native Americans and upheld the treaties he created. Penn negotiated rights to the land needed and was also to live among native tribes to create peace.