How was the Muslim siege of the town of caffa one of the first examples of germ warfare? How did it begin the spread of the Black Death to Europe?

These embers of hatred would burst into flames in 1343 in the city of Tana. After a fight between Genoese Christians and the local Muslims in Tana, one Muslim local was found dead. ... So, in 1343, the Mongols laid siege to the city of Caffa. Caffa did not turn out to be as feeble as the Mongols expected.

Explanation:

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in february 1787, congress decided that a convention should be convened to revise the articles of confederation, the nation’s first constitution. in may, 55 delegates came to philadelphia, and the constitutional convention began. debates erupted over representation in congress, over slavery, and over the new executive branch. the debates continued through four hot and muggy months. but eventually the delegates reached compromises, and on september 17, they produced the u.s. constitution, replacing the articles with the governing document that has functioned effectively for more than 200 years.

which specific shipwreck are you talking about?