Was america's division over slavery a relitively new issue or an old issue in the early 1800s?

It was an relitively old issue in the early 1800s because it had been going on for quit a while before the early 1800s 

Cherokee  removal, part of the trail of tears, refers to the  forced  relocation between 1836 and 1839 of thecherokee  nation from  their lands ingeorgia, south carolina, north carolina, tennessee, texas, and alabama to the indian territory (present day oklahoma)  in  the thenwestern united states, and the resultant deaths