Which were issues or events that led t civil war in england

Religion was an extreme part of the "English Civil War." This was a problem because the King was deeply religious while others were not, which caused some problems. Another issue that led to the "English Civil War" was the fact that the King, King Charles the 1st, started ignoring the Parliament when making laws, which angered many people. 
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The constant presence of diseases or infectious agents within a given geographic area or population group. it may also refer to the usual prevalence of a given disease with such area or group. it includes holoendemic and hyperendemic diseases. a holoendemic disease is one for which a high prevalent level of infection begins early in life and affects most of the child population, leading to a state of equilibrium such that the adult population shows evidence of the disease much less commonly than do children (malaria in many communities is a holoendemic disease). a hyperendemic disease is one that is constantly present at a high incidence and/or prevalence rate and affects all groups equally. so probably family history.