Which was not a major southern argument presented in the great debate?

losing control in congress
an antislavery coalition in government
lack of extension of cotton lands
add additional states from the southwestern lands

The best and most correct answer among the choices provided by the question is the fourth choice. Adding additional states from the southwestern lands was not a major Southern argument presented in the Great Debate. I hope my answer has come to your help. God bless and have a nice day ahead!