What occurred at Appomattox Court House?

The Battle of Appomattox Court House was fought on April 9, 1865, near the town of Appomattox Court House, Virginia, and led to Confederate General Robert E. Lee's surrender of his Army of Northern Virginia to Union General Ulysses S. Grant

The constant presence of diseases or infectious agents within a given geographic area or population group. it may also refer to the usual prevalence of a given disease with such area or group. it includes holoendemic and hyperendemic diseases. a holoendemic disease is one for which a high prevalent level of infection begins early in life and affects most of the child population, leading to a state of equilibrium such that the adult population shows evidence of the disease much less commonly than do children (malaria in many communities is a holoendemic disease). a hyperendemic disease is one that is constantly present at a high incidence and/or prevalence rate and affects all groups equally. so probably family history.