What did Eleanor Roosevelt do that made her a politician in her own right?
Restate the question

dirty, contaminated water

contaminated food,

chlostrophobic living spaces,

mice infestation,

etc,

the conditions that made the byzantine empire vulnerable to attacks by the muslin turks were the sack of constantinople by western crusaders, the conquests of the sultanate of rum, presence of rival kingdoms and finally the set up of fiefdoms at the empire which were owned by the ghazis (turkish warriors).

what are you options

declare war, appoint military officers, sign treaties, make alliances