Who was the most powerful american opponent of the treaty

It was Henry Cabot Lodge

The Irreconcilables were bitter opponents of the Treaty of Versailles in the United States in 1919. Specifically, the term refers to about 12 to 18 United States Senators, both Republicans and Democrats, who fought intensely to defeat the ratification of the treaty by the Senate in 1919.

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Explanation:

it was important because it showed that america was a force to be reckoned with during the cold war.

the end of the gilded age coincided with the panic of 1893, a deep depression, which lasted until 1897 and marked a major political realignment in the election of 1896. this productive but divisive era was followed by the progressive era.