How did disease impact the American Indians?

Many Native American tribes suffered high mortality and depopulation, averaging 25–50% of the tribes' members lost to disease.

Explanation:

the church governed the society after the empire fell.   constantine took charge of rome and ended the confusion which had over religion and made christianity as the only religion and that started ruling the roman empire. he also divided the empire into two and fortified the eastern part.   he ruled the eastern part.