Afilibuster to block a vote on a bill is possible?

Yes it is possible. Under the new rules, if senators wish to block a bill or nominee after the motion to proceed, they will need to be present in the Senate and debate.Following the changes, 60 votes are still required to overcome a filibuster to pass legislation and confirm nominees and the "silent filibuster"—where senators can filibuster even if they leave the floor—remained in place

Only in the senate which is almost unrestrained

Iwill support us side.