The reason Alexander the Great never saw the unification of his great empire was because of what tragic event?

It was his death in June 323 BCE.

Explanation:

By 323 B.C., Alexander was head of an enormous empire and had recovered from the devastating loss of his friend Hephaestion—who was also reputed to be one of Alexander’s homosexual male lovers.  Thanks to his insatiable urge for world supremacy, he started plans to conquer Arabia. But he’d never live to see it happen. After surviving battle after fierce battle, Alexander the Great died in June 323 B.C. at age 32.

answer; philip morin freneau