Discuss how colonial settlement affected native americans. make a top five list of the most impactful changes to native american populations, with #1 causing the most change and #5 causing the least change. you will also explain your reasoning for your #1.

The most impactful changes to Native American populations done by the colonial settlement was:  

1 - the disease - smallpox and influenza killed almost 90% American Native population 
2. extermination policies - by hunting them, the population was in decline
3. Territory - the colonists took their land
4. forced relocation policies - the colonits forced them to stay in some special place, no leaving, starving them
5. coexistence reasoning - the differences between colonist and Native believes