Which of the following describes nullification? a strong loyalty to a state or region, sometimes at the expense of a nation
the idea that states have powers separate from the federal government
the idea that a state could refuse to follow a federal law it disagreed with
a system that divides power between national and state governments

The idea that a state could refuse to follow a federal law it disagreed with

Explanation:

Nullification is the theory that states could refuse to follow federal laws that they disagreed with.

One example of this is the Nullification Crisis between South Carolina and the US government, over the Tariff of 1828, also called the Tariff of Abominations.

The state, under leadership of John C Calhoun, tried to nullify the tariff because it would hurt the Southern economy.

the doctrine of nullification recommended that states living inside the union have the one-sided, inalienable ideal to void any law made by the national government that could be esteemed illegal.

the united states was shaped based on a general agreement among its individual states. hence, it is inferred that under the hypothesis of invalidation, since the states are the establishment of the union, they have the ability to referee and disprove unlawful laws.

to protest slavery i would think it would be a