Why did the Missouri compromise of 1820 and 1850 fall apart?

Missouri Compromise, (1820), in U.S. history, measure worked out between the North and the South and passed by the U.S. Congress that allowed for admission of Missouri as the 24th state (1821). It was  marked the beginning of the prolonged sectional conflict over the extension of slavery that had led to the American Civil War.

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a system in which products were made rapidly by machines

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explanation: