Constantine moved the capital of the Empire

In the year 330 CE, the Emperor Constantine decided to move the seat of the government from Rome to Byzantium, which was renamed Constantinople. The founding of Constantinople led to it becoming the focal point of the Silk Trade Routes and to Istanbul becoming a major city in the world.Population also was affected by this move, Byzantium (which ultimately became Constantinople) was just a village before Constantine had his "vision" to build another capital there, after the administrative workers and artisans and merchants moved there, Rome started to lose its intellectual population, leaving behind.The founder of the Byzantine Empire and its first emperor, Constantine the Great, moved the capital of the Roman Empire to the city of Byzantium in 330 CE, and renamed it Constantinople. Constantine the Great also legalized Christianity, which had previously been persecuted in the Roman Empire.Constantinople was the largest and richest urban center in the Eastern Mediterranean Sea during the late Eastern Roman Empire, mostly as a result of its strategic position commanding the trade routes between the Aegean Sea and the Black Sea. Constantinople is an ancient city in modern-day Turkey that's now known as Istanbul. ... In 330 A.D., it became the site of Roman Emperor Constantine's “New Rome,” a Christian city of immense wealth and magnificent architecture.

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this act gave the federal government the power to relocate any native in the east to territory west of the mississippi river.

a. always outside of government control.