A major difference between the Zapotec civilization and the ancient Egyptians is that

A)
the Egyptians had no access to trade.

B)
the Zapotecs were not located around a major river.

C)
the Zapotecs were able to build complex structures.

D)
the Egyptians could not create a succession of rulers.

B) the zapotecs were not located around the major river

Explanation: The Zapotecs, known as the 'Cloud People', dwelt in the southern highlands of central Mesoamerica, specifically, in the Valley of Oaxaca, which they inhabited from the late Preclassic period to the end of the Classic period (500 BCE - 900 CE). Their capital was first at Monte Albán and then at Mitla, they dominated the southern highlands, spoke a variation of the Oto-Zapotecan language, and profited from trade and cultural links with the Olmec, Teotihuacan and Maya civilizations.  

B)  the Zapotecs were not located around a major river.

Explanation: The Zapotec civilization was an indigenous pre-Columbian civilization that flourished in the Valley of Oaxaca in Mesoamerica. Archaeological evidence shows that their culture goes back at least 2,500 years. The Zapotec left archaeological evidence at the ancient city of Monte Albán in the form of buildings, ball courts, magnificent tombs and grave goods including finely worked gold jewelry. Monte Albán was one of the first major cities in Mesoamerica and the center of a Zapotec state.

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the answer to your question is c