How did the border dispute between Mexico and Texas effect the Mexican-American war

Need on these last 2 questions on my social studies homework 5 and 6 then i’m done with the homework

Which is likely the most serious problem associated with an epidemic? 1. there are sometimes no cures to the diseases that spread. 2. people often die from the diseases that spread. 3. there are usually no ways to prevent people from getting ill. 4. people often don’t know they have a disease.

Why did noli me tangere have such a big impression on the narrator?