Whats the definition of interstate commerce?

Why is james madison significant in regards to the bill of rights?

What was significant about the election of 1828 a. it was first to include b. it was first under new voting reforms c. it reintroduced the two party system d. it was decided by members of congress

Plz although president washington was not a member of the federalist party or the republican party his closest relationship was with, a. john adams. b. james madison. c. alexander hamilton. d. thomas jefferson.