How did the united states get access to the canal zone in panama? spain gave control of columbia and the canal area to the u. s. government. the u. s. military took control of the area by using money and investments. panama negotiated with the united states to become an independent country. the u. s. military backed rebels who soon controlled independent panama.

The constant presence of diseases or infectious agents within a given geographic area or population group. it may also refer to the usual prevalence of a given disease with such area or group. it includes holoendemic and hyperendemic diseases. a holoendemic disease is one for which a high prevalent level of infection begins early in life and affects most of the child population, leading to a state of equilibrium such that the adult population shows evidence of the disease much less commonly than do children (malaria in many communities is a holoendemic disease). a hyperendemic disease is one that is constantly present at a high incidence and/or prevalence rate and affects all groups equally. so probably family history.