What did socrates belive came from ignorance?

He among you is the wisest who, like Socrates, knows that his wisdom is really worth nothing at all.

What does it mean? Socrates spoke with a man who was said by many to be wise, but found that this man, like countless others he had spoken to, had no more wisdom than Socrates had, [and that the man even became angry and refused to acknowledge his ignorance when Socrates showed him that this was so,] and therefore Socrates concluded that "it seems I am wiser than he is to this small extent, that I do not think I know what I do not know".

In other words, despite that all Socrates knows is that he has no wisdom, his wisdom isn't really "worth nothing at all". That is the paradox of Socratic ignorance.

they died because of a disease during the first spanish colonies.

this is a good question! i'll do some research and come back when i have the answer!