What signs would you look for in order to tell if a particular medicine or treatment was a fake cure? how can you avoid quackery?

You can check the labels on the bottle or even ask you doctors

Pretty bad i would assume.

Depression is lifelong, though you can get medication to with it. the difference between sadness and depression is that sadness lasts a little bit, depression last a long time and it goes on and off. people usually get depression through experiences they have been through, or genetics.