Whenever someone tells me to ‘Just be happy,’ I want to yell, ‘Oh, hey, depression’s gone! Why didn’t I think of that?’ But usually I just roll my eyes instead. It’s so difficult to describe depression to someone who’s never been there, because it’s not sadness. I know sadness. Sadness is to cry and to feel. But it’s that cold absence of feeling—that really hollowed-out feeling. What they don’t tell you about depression is that sometimes it feels a lot less like sadness and a lot more like the emotional equivalent of watching paint dry. The only thing more exhausting than being depressed is pretending that you’re not. Sometimes I just think depression’s one way of coping with the world. Like, some people get drunk, some people do drugs, some people get depressed. Because there’s so much stuff out there that you have to do something to deal with it.

Poliovirus is an rna virus of the picornavirus group, which uses its rna as mrna. at its 5' end, the rna genome has a viral protein (vpg) instead of a cap. this is followed by anontranslated leader sequence, and then a single long protein-coding region (~7000 nucleotides), followed by a poly-a tail. observations were made that used radioactive amino acid analogues. short period use of the radioactive amino acids result in labeling of only very long proteins, while longer periods of labeling result in several different short polypeptides. what conclusion is most consistent with the results of the radioactive labeling experiment? a) host cell ribosomes only translate the viral code into short polypeptides.b) the rna is only translated into a single long polypeptide, which is then cleaved into shorter ones.c) the rna is translated into short polypeptides, which are subsequently assembled into large ones.d) the large radioactive polypeptides are coded by the host, whereas the short ones are coded for by the virus.