Which endocrine diseases can lead to secondary diabetes? Explain the mechanism in each case.​

Endocrine diseases such as acromegaly, Cushing's syndrome and pheochromocytoma can increase glucose production and cause insulin resistance. Hyperthyroidism, hyperaldosteronism, glucagonoma and somatostatinoma lead to hyperglycemia by other physiopathological mechanisms detailed in this article.

The most common causes of secondary diabetes are as follows: Diseases of the pancreas that destroy the pancreatic beta cells (eg, hemochromatosis, pancreatitis, cystic fibrosis, pancreatic cancer) Hormonal syndromes that interfere with insulin secretion (eg, pheochromocytoma)

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