Long-term effects of alcohol on the body include:

A.) All the above

Explanation:  Drinking too much alcohol can cause abnormal activation of digestive enzymes produced by the pancreas. Alcohol puts the brakes on your immune system. Your body can't make the numbers of white blood cells it needs to fight germs. So for 24 hours after drinking, you're more likely to get sick. Long-term, heavy drinkers are much more likely to get illnesses.

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exercising at a moderate intensity, and slowly increasing the duration.