2. A 50-kg woman was given a single IV dose of an antibacterial drug at a dose level of 6 mg/kg.
Blood samples were taken at various time inter-
vals. The concentration of the drug (Cp) was
determined in the plasma fraction of each blood
sample and the following data were obtained:
One-Com
a. What are the values for Vp, k, and in for this
drug?
b. This antibacterial agent is not effective
at a plasma concentration of less than
2 ug/mL. What is the duration of activity
for this drug?
e. How long would it take for 99.9% of this
drug to be eliminated?