A doctor confirms that a patient is overweight after performing multiple tests and calculating the patient’s body mass index (BMI). Which strategy will the doctor most likely recommend to help the patient reduce his weight in a healthy way? a)Follow a workout plan if there is extra time in the day. b)Eat one serving of fruit each week. c)Follow a diet that increases food consumption. d)Join a weight-loss support group.

Adouble-blinded trial for a new indication is conducted under an ind comparing two (2) marketed drugs, at twice the approved prescribed doses. on day 2, subject 603 had difficulty breathing. although it was life-threatening initially, subject 603 was treated and discharged directly from the emergency department after complete recovery. on day 5, subject 20 had a headache, which led to hospitalization and required blood pressure lowering medications. these episodes cannot be explained on the basis of the pharmacological property of either drug or the subjects' medical histories. the investigator would submit an sae report for